Criblage antibactérien de six plantes médicinales du Cameroun vis-à- vis des bactéries Gram Négatif multirésistantes : Identification des principes actifs de Acacia polyacantha (Euphorbiaceae) et leur mode d’action

Abstract

Bacterial infections, especially those caused by multidrug-resistant Gram-negative bacteria are a real public health problem around the world. Faced with this scourge, natural substances derived from medicinal plants could constitute an alternative to antibiotics, given the rich biodiversity of the plant world. The purpose of the present study is to evaluate the antibacterial activity of six medicinal plants from Cameroon (Acacia polyacantha, Alchornea cordifolia, Eremomastax speciosa, Laportea aestuans, Pennisetum purpureum and Spathodea campanulata), against multi-resistant Gram-negative bacteria as well as the identification of the active ingredients of Acacia polyacantha (Euphorbiaceae) and their mode of action.