Étude comparative des transaminases chez quelques femmes obèses de Yaoundé avec syndrome métabolique ou non

Abstract

Background and aims: Both Metabolic syndrome (MS) and obesity are important public health issues around the world because of their impact on cardiovascular mortality. Generally it is considered that Transaminases level are elevated in metabolic syndrome. Scarce data in different population exist, this study aim to compare transaminases level among obese women with MS and their counterpart. Methods: 662 obese women living in Yaoundé were recruited during free chronic diseases campaign from march 2014 to march 2016 at Fouda Medical Center. MS was diagnosed according to national cholesterol education program adult treatment III 2001 definition. In that sample, 100 obese women with MS and 100 others without MS were randomly selected for transaminases evaluation. Keys results: All studied parameters were significantly (P<0.05) increased among Obese women with metabolic syndrome except for HDL cholesterol. The prevalence of MS was 20.90% and the most frequent individual component were abdominal obesity (60.27%), high triglycerides (33.38%) and hyperglyceamia (18.88%). The Transaminases level was significantly (P<0.05) increased among obese women with MS comparatively to their counterpart. Conclusion: MS is common among obese women of Yaoundé and transaminases can be considered as a marker of metabolic syndrome.